Findings seen in patients previously treated with platinum-based chemotherapy and immunotherapy whose tumors highly expressed CEACAM5

Significant benefit seen for neoadjuvant tislelizumab plus chemotherapy with adjuvant tislelizumab

Improved median overall survival and progression-free survival seen for pegargiminase-based chemotherapy

Increased radiation with SABR boost seems to enhance local control but with reduced overall survival at highest dose

Greater incidence of grade 3 or higher adverse events from any cause seen in combination group versus monotherapy

Improvement in overall survival seen for patients receiving cisplatin or carboplatin with pemetrexed

First-line atezolizumab monotherapy is associated with improved overall survival compared with single-agent chemotherapy

Improvement seen compared with chemotherapy alone for first-line treatment of advanced non-small cell lung cancer

Integration of definitive local therapy relevant if technically feasible and clinically safe to all disease sites

<p style="margin-left: 20px;">Progression-free survival significantly longer with tislelizumab plus chemotherapy versus chemotherapy alone