Alternative criteria included people who smoked any amount for at least 40 years; people aged 60 to 80 years with 40 pack-years of smoking
Similar findings seen for those who previously used combustible cigarettes and currently use electronic cigarettes
Increase in UTD-LCS prevalence seen with age and number of comorbidities; relatively lower levels seen in Southern states
Uptake of lung cancer screening was low, but overall and lung cancer-specific survival improved with screening
Of those newly eligible under 2021 criteria, 2,063,840 were aged 50 to 54 years and 4,020,879 had 20 to 29-pack-year smoking history
Updated guidelines recommend annual screening for those aged 50 to 80 years who currently smoke, or formerly smoked
PLCOm2012 models have higher sensitivity than USPSTF criteria, with no difference by Indigenous classification
Model relies only on age, smoking duration, and pack-years
Meta-analysis only shows a 110-day survival benefit for colorectal cancer screening with sigmoidoscopy
Single-site cancer screening could save an additional 3.2 to 5.1 million life-years with perfect adherence